Meanwhile, cut broccoli into small, bite-sized pieces; add to pasta during the last 3-4 minutes of cooking. Drain.
Melt butter in a large skillet over medium. Whisk in the flour and cook until slightly brown, approximately 1 minute. Gradually whisk in the broth and milk; continue to cook for 1-2 minutes, stirring constantly.
Add cream, garlic powder, and Italian seasoning; whisk together until slightly thickened. Stir in 1/3 cup Parmesan, then add pasta and broccoli. Stir to combine then remove from heat.
Serve pasta topped with additional Parmesan; serve orange wedges on the side.