Heat a large skillet over medium; add the ground turkey. Stir to brown and break into smaller pieces; allow to cook for 5 minutes.

Dice onion, mince garlic, and add both to the skillet. Cook until turkey is no longer pink, then add to slow cooker. Stir in broth, tomatoes, ketchup, Worcestershire sauce, brown sugar and Italian seasoning. Cover and cook on low for 8-10 hours.

Add pasta about 25 minutes before you're ready for dinner. Cook for 25 minutes or until noodles have softened. Season with salt and pepper to taste.